Endocrine Abstracts

It has been generally believed that clinically functioning pituitary adenomas are highly specialized neoplastic lesions, which produce a unique hormone. Increasing body of evidence argue against this concept, since about half of prolactinomas (PRM) and approximately 60% of TSH-secreting adenomas are multihormonal and 30–40% of GH-secreting adenomas co-secrete PRL. Most of classically considered null cell adenomas have been proved to be immunohistochemical positive for gon...